CAT and atherosclerosis: The active organelle-targeted system can be readily expanded to other types of catalytic entities (e.g., catalase), chemotactic molecules (e.g., dequalinium chloride), and organelles (e.g., nucleus, lysosome, and endoplasmic reticulum) toward the treatment of broader pathologies, such as neurodegenerative diseases (66) and atherosclerosis (67).