Quantitative analysis of Masson trichrome, Sirius red and SMA revealed that histopathologically diagnosed with pulmonary fibrosis post-surgery in control and COVID-19 patient cohorts present significant higher collagen depots and increased presence of activated fibroblasts and/or myofibroblasts as compared to control lungs (Figure 3A–3D). Here, SMN1 is linked to COVID-19.