BCL11B and neoplasm: For instance, BCL11B upregulation has been reported in Ewing sarcoma to maintain its oncogenic character18; the expression of BCL11B has been found to be correlated with the poorly differentiated tumor status of head and neck squamous cell carcinoma19; enriched expression of BCL11B in glioma cells promotes cell growth20; and BCL11B suppression using RNA interference technique inhibited leukemic T cells proliferation by apoptosis.21