CP and type 2 diabetes mellitus: Megamonas was negatively correlated with conjugated BAs (GCA and GLCA), but positively associated with SCFAs (HA) and unconjugated BAs (β-MCA and CA) (Figures 6F, 7G).Taken together, the abovementioned results reveal that the changes in gut microbiome abundances induced by CP may be responsible for the alteration of metabolites, thus affecting metabolic phenotypes in patients with T2DM.