Dysregulated protein synthesis has emerged as a prominent process implicated in several monogenic forms of ASD and intellectual disability (Chen et al., 2019), as well as in sporadic ASD (Hooshmandi et al., 2020), and is often accompanied by changes in key signaling pathways upstream of translation such as mTOR (Rosina et al., 2019). This evidence concerns the gene MTOR and Intellectual disability.