In line with this, Lu and collegues concluded that inhibition of bromodomain-containing protein 4 (BRD4) in TNBC cell lines regulates SNAI1 in a PKD1-dependent manner, resulting in decreased migration and invasion in breast cancer cells and reduced tumor growth and metastasis in xenograft models (Lu et al., 2020). This evidence concerns the gene PKD1 and breast carcinoma.