As anticipated BN-PAGE revealed relatively increased (57% versus 44%) ATP5A MCs (≥720 kDa) but relatively unaltered (63% versus 62%) UQCRC2 MCs (≥720 kDa) in CHRM1 reduced AD hippocampus compared to the CHRM1 positive non-demented individual (Figures 4C, D, red dotted brackets). Here, CHRM1 is linked to Alzheimer disease.