Phenotypes associated with variant forms of genes of aerobic metabolism represented abnormalities such as ‘impaired glucose tolerance’ (MP:0005293), ‘decreased insulin secretion’ (MP:0003059), ‘increased circulating lactate level’ (MP:0013405), and ‘ketosis’ (MP:0030970) (a phenotype associated with rapid lipid breakdown). Here, INS is linked to Impaired glucose tolerance.