Biochemical and imaging findings, including des-gamma-carboxy prothrombin (DCP), alpha fetoprotein (AFP) levels, disruption of the capsule, irregular tumor margin, peritumoral enhancement, multifocal tumor, increased tumor size, tumor differentiation, multilobar involvement, increased glucose metabolism on positron emission tomography-computed tomography, and Milan criteria, have either been variable or controversial [11, 14–18]. The gene discussed is AFP; the disease is neoplasm.