Implantation site number was no different between the PEG and PEGIL11-treated animals on E13 or E17 (Figure 5K), but there were significantly fewer pups born alive to PEGIL11-treated Asc-/- mice (Figure 5G), suggesting PEGIL11 treatment caused late-gestation fetal loss or stillbirth in this genetic background. Here, PYCARD is linked to Stillbirth.