The levels of inflammatory mediators in the nasal mucus of OD and NOD participants were measured by CBA assays, showing that the levels of IL-5, IL-8, MIP-1α, MCP-1, and TNF were significantly higher in the OD group than in the NOD group (P = 0.030, P = 0.025, P = 0.031, P = 0.019, and P = 0.029, respectively, Figure 6A and Supplementary Table S4). This evidence concerns the gene IL5 and osteochondritis dissecans.