Since glycemic control and its predictors have become the topmost concern in the management of T2DM patients as morbidity and mortality in T2DM are believed to be due in large part to the direct consequences of chronic hyperglycemia, our results will provide a stimulus for further exploration of the potential discriminant predictive potential of PAI‐1 in this field. The gene discussed is SERPINE1; the disease is type 2 diabetes mellitus.