SERPINE1 and type 2 diabetes mellitus: On the contrary, Nkansah et al.17in their study recorded a significantly higher plasma level of PAI‐1 antigen and activity in T2DM patients than controls, and this disparity could be due to genetic variations between our study groups as other genetic studies indicated that polymorphisms in PAI‐1 gene (genetic variants) influence the plasma levels of the antigen.27, 28