The results revealed significantly prolonged progression-free survival of the tiragolumab plus atezolizumab arm in the total population (HR 0.62; 95% CI 0.42–0.91) and in patients with PD-L1 tumor proportion score (TPS) ≥ 50% (HR 0.29; 95% CI 0.15–0.53). This evidence concerns the gene CD274 and neoplasm.