For example, miR-200a targets TFAP2C mRNA [163], miR-200b suppresses TFAP2A expression in cholangiocarcinoma [36], miR-3960 suppresses TFAP2A mRNA in the pancreatic cancer [164], and miR-27a inhibits TFAP2B mRNA in HCC [55]. The gene discussed is TFAP2A; the disease is familial pancreatic carcinoma.