In NSCLC, LncRNA PP7080 promotes the phosphorylation of TFAP2C, which then upregulates the expression of programmed cell death protein 6 (PDCD6) to promote cancer cell malignancy and to induce immune-suppressive tumor microenvironment by recruiting myeloid-derived suppressor cells [82]. This evidence concerns the gene TFAP2C and non-small cell lung carcinoma.