According to the molecular classification standard of breast cancer, among the 46 patients who clearly provided the expression conditions of Her-2 and HR, Her-2(+) and HR (-) 17 cases (36.96%) were tri-negative breast cancer 11 cases (23.91%) were luminal A breast cancer 8 cases (17.39%) were luminal B breast cancer 10 cases (21.74%) (Table 4). Here, ERBB2 is linked to breast carcinoma.