CTSB and cancer: Reportedly, CCNT1 is related to T lymphocyte differentiation and malignant transformation by interacting with CDK9 [20]; CNDP2 is a nonspecific metallopeptidase for the hydrolysis of carnosine and several other dipeptides [21]; CTSB is a lysosomal cysteine endopeptidase and associated with metastasis of cancer cells [22].