To explore the potential utilization of EBV-related antibodies in gastric cancer screening and diagnosis, we analysed the association between Epstein-Barr nuclear antigen 1 immunoglobulin A (EBNA1-IgA) and viral capsid antigen immunoglobulin A (VCA-IgA) in sera and the risk of gastric cancer in a population-based nested case-control study in Zhongshan, a city of southern China. Here, CD79A is linked to gastric cancer.