As well as increasing age, smoking history, BMI, and increasing copies of MUC5B promoter polymorphism being predictive background factors for ILA progression [3, 6, 11], the fibrotic signs of lung distortion, traction bronchiolectasis/bronchiectasis, and honeycombing on HRCT imaging are considered to be crucial for the progression of ILA and poor prognosis [10, 12, 17, 18]. Here, MUC5B is linked to bronchiectasis.