Of interest is V genes associated with autoimmunity appear to be preferred in certain sequence subsets in some tumors compared to both healthy volunteers’ blood and tonsil samples (e.g., IGHV6-143: 85.71% of IgA1, patient P71; IGHV1-6944: 63.6% of IgM, patient P58, 65.9% and 31.5% of IgG1 in patient P55 and P58, respectively; IGHV4-3444: 42.1% of IgG2, patient P84; IGHV4-3944: 32.6% of IgM, patient P71). The gene discussed is IGHA1; the disease is Autoimmunity.