Multivariate analysis showed that GPR176 (HR = 1.80, P = 0.003), residual tumor (HR = 2.81, P < 0.001), and age (HR = 1.55, P = 0.027) were independent prognostic factors for GC (see Supplementary Fig. S1b online, Table 1). Here, GPR176 is linked to neoplasm.