GPR176 and cancer: GSEA showed that compared to the GPR176 low expression group, the GPR176 high expression group was enriched considerably in two cancer-related signaling pathways: TGF_BETA_SIGNALING_PATHWAY, MAPK_SIGNALING_PATHWAY, and four immune-related signaling pathways: COMPLEMENT_AND_COAGULATION_CASCADES, CHEMOKINE_SIGNALING_PATHWAY, CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION, and JAK_STAT_SIGNALING_PATHWAY (Fig. 3c, see Supplementary Table S2 online).