In line with the increase in numbers, Ki-67 staining revealed that CD24hiIgDlo/–CD38lo and CD24hiIgDlo/−CD38hi Bregs in tumor-bearing mice showed greater proliferation than those in naïve mice, which was further increased by FGK and inhibited by GSK (Supplementary Fig. S6a). The gene discussed is MKI67; the disease is neoplasm.