PIK3CA and cancer: Examining the RNA-protein correlation of PIK3CA in each of these three cancer types, divided into patients with and without PIK3CA alteration (i.e. mutation or copy number aberration), we found that in PIK3CA amplified tumors (in LUSC), the RNA-protein correlation is higher than in non-amplified tumors (0.76 vs. 0.45; Fig. 2B).