CD4 and type 1 diabetes mellitus: For example, type 1 diabetes (T1D)-associated variants were enriched in T cell caQTLs (activated CD4+ T logOR = 1.62, p = 0.017; naive CD8+ T logOR = 2.1, p = 0.030), where T cells are the critical cell type in the pathogenesis of T1D [31].