POU4F3 and sensorineural hearing loss disorder: Sensorineural hearing loss (SNHL) is one of the most common congenital disorders and affects more than 1 in 1,000 newborns.3,4 Hereditary SNHL can be attributed to either syndromic or nonsyndromic genetic causes.5,6 On the basis of the partial overlap of gene expression between the cochlea and the vestibular organs, it is not surprising that mutations in these deafness genes may also cause vestibular dysfunction, as seen in patients with DNFA9, DFNA11, DFNA15, and Usher syndrome.7