The final joint model showed that 10-year age increase; history of smoking; history of diabetes, CVD, or PVD; 5 mL/min/1.73 m2 eGFR decrease; 5 g/L serum albumin decrease; 0.1 mmol/L phosphate increase; and doubling of parathyroid hormone levels or urinary protein:creatinine ratio significantly increased ACM risk (Table 2). This evidence concerns the gene PTH and diabetes mellitus.