The previous characterization of M35 indicated an antagonism of M35 with NF-κB based on (i) M35-mediated downmodulation of induction of an artificial NF-κB luciferase reporter and (ii) correlation of M35’s phenotype with reduced levels of proinflammatory TNF-α in macrophages at 16 h post-infection. Here, NFKB1 is linked to infection.