CCAAT enhancer binding protein beta (CEBPB), runt-related transcription factor 1 (RUNX-1), transforming growth factor-beta (TGF-β) receptor type 2 (TGFBR2), interferon-regulatory factor (IRF) 6, and IRF7 are important transcription factor–associated genes and showed similar expression patterns in AML cells and HAM relative to MDM (Fig. 4G). Here, RUNX1 is linked to acute myeloid leukemia.