Hence, the in vivo experiments were carried out by establishing caecal ligation and puncture (CLP) model to explore the influences of PMS in lung, liver and heart tissues, as well as unearthed the anti-inflammatory and anti-apoptosis effects of PMS in sepsis and TNF receptor associated factor 6 (TRAF6)/NF-κB regulated mechanism. This evidence concerns the gene TRAF6 and Sepsis.