Figure 8I identifies the inverse association between RNF112 and FOXM1 in gastric cancer tissues. We next investigated the protein expression of FOXM1, RNF112, CKS1, and ZEB1 in 12 pairs of gastric cancer tissues and corresponding noncancerous, adjacent tissues (Supplemental Figure 11B). The results revealed that RNF112 protein expression was negatively correlated with that of FOXM1, CKS1, and ZEB1 (Supplemental Figure 11C), suggesting the presence of the RNF112/FOXM1 pathway in vivo. Here, ZEB1 is linked to gastric cancer.