SERPING1 and angioedema: Consistent with this notion, Bork and colleagues reported that the mean duration of angioedema episodes in patients with Plg-Glu311 was substantially longer after C1-INH infusion (mean duration decrease from 48.2 +/−32.5 h untreated to 31.5 +/−8.6 h treated) than with the B2 receptor antagonist icatibant (mean duration decrease from 44.7+/−28.6 h untreated compared with to 4.3 +/−2.6 h treated) (Bork et al., 2020b).