•Analysis of human AAA mRNA microarray dataset identified DEGs, which were then used to construct a PPI network revealing 3 genes previously reported to be associated with AAA, and 3 novel genes. The Ang II murine AAA scRNA-seq database was analyzed for these results, revealing 4 AAA-linked genes in common—CANX, CD44, STAT1, and DAXX. This evidence concerns the gene CANX and triple-A syndrome.