Study in South Africa. The median age of PLWH with SARS-CoV-2 infection- 46 Male sex- 29.1% Median CD4 count- 267 Patients admitted- 255 Patients discharged- 195 Patients died- 60 Patients on ART-169 (88%) Patients on ART having AIDS-73 (28%) Smoking risk ratio- 2.86 Neutrophilia risk ratio-1.024 HbA1c risk ratio- 1.01 The gene discussed is CD4; the disease is AIDS.