Although some scholars have speculated that antiretroviral drugs may favor HIV patients due to their activity against SARS-CoV-2 and other coronaviruses, there has been no evidence that HIV patients receiving certain antiretroviral drugs have an altered risk of COVID-19 infection and severity [64,65]. A study found that older age, late diagnosis, low CD4 cell count, and treatment-naive status were potential determinants of COVID-19 incidence among HIV patients. This evidence concerns the gene CD4 and COVID-19.