RELN and myelodysplastic syndrome: A recent study analyzed a three‐generation pedigree with dominantly inherited MDS and identified KCNN2 as another causative gene.[86] After excluding the established genetic causes of MDS (SGCE and KCTD17) and several other potentially related genes (including SCN8A and RELN), a heterozygous missense variant of KCNN2 was found to segregate with disease status.