SGCE and myelodysplastic syndrome: Multiple isoforms of SGCE, including a brain‐specific one (exon 11b), are expressed in humans.[70] Different isoforms have also been identified in pre‐ and postsynaptic compartments.[71] This multitude of isoforms suggests the complex roles of SGCE in neuronal biology, and a variety of cellular processes—such as calcium homeostasis, membrane stabilization, and cell cycle control—have been implicated in its functioning.[72, 73] Despite these findings, the relevance of these isoforms to the pathogenesis of MDS remains obscure.