Cardiac-specific CYP2J2 overexpression had beneficial effects on cardiovascular disease progression and recovery, such as improving the outcomes of ischemia and/or ischemia‒reperfusion injuries, decreasing arrhythmia of hypertension and delaying hypertension development (Xiao et al., 2010; Islam et al., 2017; Aliwarga et al., 2018). This evidence concerns the gene CYP2J2 and Hypertension.