Dominant TCRα and dominant TCRβ chains were identified, TRAV26-1*01-J12*01 was paired with TRBV3-1*01-D1*01-J2-7*01 in B13.1 TILs group, TRAV5*01-J6*01 was paired with TRBV7-9*01-D1*01-J2-1*01 in B13.4 TILs group, and TRAV3*01-J10*01 was paired with TRBV19*01-D1*01-J1-6*02 in B13.14 TILs (Table 1), which suggested that the first ranked TCR could be most likely tumor-reactive TCR. The gene discussed is TRBV19; the disease is neoplasm.