SEMA4D expression was negatively correlated with MSI in most tumors, including LIHC, mesothelioma (MESO), PAAD, rectum adenocarcinoma (READ), SKCM, TGCT, and UCS, but was positively correlated with MSI in BRCA, CESC, LUAD, and UCEC (Figure 7B). Here, SEMA4D is linked to rectum adenocarcinoma.