CDCA5 and neoplasm: For instance, Fu et al. discovered that CDCA5 may control the cell cycle, the Phosphoinositide 3-kinase (PI3K)/v-akt murine thymoma viral oncogene homolog 1 (AKT)/mechanistic target of rapamycin (mTOR) pathway, and dysregulated mitochondria-mediated apoptosis to operate as a tumor promoter in bladder cancer [7].