MBOAT4 and obesity due to melanocortin 4 receptor deficiency: Chronic administration of an oral GOAT inhibitor (GLWL-01) over 28 days, which markedly decreased plasma AG in adults with obesity and type 2 diabetes mellitus also had no effect on body weight (though this is complicated by plasma AG being low already in obesity) (https://clinicaltrials.gov/ct2/show/results/NCT02377362).