MGLL and migraine disorder: Based on this premise and work suggesting MAGL is implicated in a nitroglycerine model of migraine (12, 13), studies herein examined the influence of CSD induction on AEA and 2-AG levels in distinct brain areas, including V1M cortex, occipital visual motor cortex 1; PAG, periaqueductal gray; Vc, trigeminal nucleus caudalis; and TG, trigeminal ganglia.