Since β1 integrins, such as α 5β1, can bind to the ECM component fibronectin, and the presence of ECM adhesion molecule fibronectin stimulates in cultured cells the secretion of MMPs, facilitating cancer cell invasion, we investigated the effect of this important ECM protein fibronectin as well as fibrinogen and laminin on fiber displacements. Here, FN1 is linked to cancer.