ADAM8 and cancer: ADAM8 has been reported to be highly expressed in pancreas cancer (Schlomann et al., 2015; Yu et al., 2020) or ductal adenocarcinoma (Jaworek et al., 2021), is coupled to poor clinical prognosis of cancer and seems to be linked to the effect of chemoresistance to medical treatment of cancers (Conrad et al., 2019).