IL6 and Stroke: Other reports also suggested that IL‐6 plays an important role in cerebral ischemia not only as a mediator of the inflammatory process in the acute phase of stroke but also has chronic effects that might contribute to the formation and maturation of atherosclerotic plaques, which increase the risk of stroke recurrence and then resulted in functional damage as a neurotrophic factor in the late phase of the development of cerebral ischemia.7, 33