Although prior studies reported associations between the higher concentration of IL‐6 and higher risks of stroke recurrence or functional impairment,12, 13, 14, 15, 16, 17, 18 none of them quantified the extent of functional impairment resulting from IL‐6 directly or resulting from the pathway of IL‐6–stroke recurrence–functional impairment. This evidence concerns the gene IL6 and Stroke.