Fourteen transcripts (INFG, SOX2, WNT3A, FGF10, JAG1, BDNF, ICAM1, MCAM, KITLG, ITGA6, GDF15, ENG, SLC17A5 and FGF-2) were upregulated in MDS patient-derived MSCs during culture in XF media and four transcripts (NES, GDF7, ANPEP and RUNX2) were downregulated (Fig. 4B). This evidence concerns the gene BDNF and myelodysplastic syndrome.