In univariate analysis, 12 factors (extrahepatic metastasis, tumor size, tumor number, BCLC stage, Child-Paugh class, PLT, ALC, ALP, Alb, AFP, and prior surgery) were considered to be significant survival-related variables among the 33 candidate variables in the training cohort (Table 2) and further included in multivariate analysis. The gene discussed is ALB; the disease is neoplasm.