Importantly, gene sets related to the toll-like receptor signaling pathway (Fig. 2A), TLR1/2 cascade (Fig. 2B), toll endogenous pathway (Fig. 2C), TLR signaling related to MyD88 (Fig. 2D), NOD, and NLR signaling pathways (Fig. 2E, F) were significantly enriched in FFAR2DownTLR2UpTLR3Up NSCLC (Group A) vs. FFAR2UpTLR2DownTLR3Down NSCLC (Group B). This evidence concerns the gene MYD88 and non-small cell lung carcinoma.