Ying et al. [26] developed an equation based on fuzzy mathematics to assess the timing of haemodialysis initiation, the results showed that the combination of sex, age, serum creatinine, blood urea nitrogen, serum albumin, haemoglobin, serum phosphorus, diabetes mellitus, and heart failure as equation variables resulted in the best accuracy to prognose 3-year survival. The gene discussed is ALB; the disease is heart failure.