Independent factors (P < 0.05) associated with mortality in the multivariable Cox model in early dialysis start were: hypertension (HR 9.32, CI: 1.34–17.87), diabetes (HR 1.8, CI: 0.4–13.2) and albumin < 3.5 g/dL (HR 1.5, CI: 0.8–6.2). The gene discussed is ALB; the disease is hypertensive disorder.