NC (Normal Control), Testosterone propionate (TP), Fin( Finasteride), Ethanol crude Tuber extract of C. esculenta (ECTECE), Hexane fraction(HF), Dichloromethane fraction( DCMF), Butanone fraction(BF), Ethyl acetate fraction(EAF) and Aqueous Fraction (AF) and BPH( benign prostate hyperplasia), Prostate Specific Antigen( PSA). Here, KLK3 is linked to benign prostatic hyperplasia.