CDKN2B-AS1 and cancer: We conducted rescue experiments in both HCT-8 cells and HLECs, and found that PZH inhibited the migration, invasion and VEGF-C secretion of HCT-8 cells, and inhibited cancer cells supernatant-mediated HLECs lymphangiogenesis, while these inhibitory effects of PZH was attenuated by ANRIL overexpression.