Another study by Olbrich et al. [14] showed that a p53-dependent response posed a survival disadvantage to the near-haploid Chronic Myelogenous Leukemia (CML)-blast crisis cell line KBM7 (haploid for all autosomes except chromosome 8 and 30 Mb of chromosome 15, also bearing the BCR-ABL translocation t(9;22)(q34;q11)), manifested as deficiencies in chromosome segregation and failed mitosis. This evidence concerns the gene TP53 and chronic myelogenous leukemia, BCR-ABL1 positive.