BRD2 and hepatocellular carcinoma: ROC analyses computed for different comparisons show excellent biomarker properties; AUC of 0.99 for HCC versus Healthy blood (Fig. 1F), AUC of 0.97 for HCC versus all healthy and NAT tissues including liver (Fig. 1G), AUC of 0.95 for HCC samples are compared to healthy tissues (specificity-95%; sensitivity-85%), AUC of 0.92 for HCC compared to NAT (specificity-94%; sensitivity-95%), AUC of 0.966 for HCC versus healthy liver tissue (specificity-100%; sensitivity- 88%) and AUC of 0.87 for HCC versus 31 different types of cancer (Supplementary Table 1) (Fig. 1H).