In particular, CD8+ T cell infiltration was also positively correlated with high CLDN5 expression in BLCA, BRCA, KIRP, brain LGG, LIHC, PAAD, PCPG, PRAD, READ, testicular germ cell tumor (TGCT), thymoma (THYM), UCEC, and UVM (P<0.05). This evidence concerns the gene CD8A and bladder transitional cell carcinoma.