Based on the Cox regression analysis of 33 cancers (Figure 3A and Supplementary Figures 1–3), in seven cancers, including STAD, uveal melanoma (UVM), KIRP, COAD, THCA, UCEC, and PAAD, CLDN5 expression was significantly correlated with OS. This evidence concerns the gene CLDN5 and pancreatic adenocarcinoma.